Job Title

Position DescriptionPerforms specialized post-doctoral work in the planning, conducting and/or supervision of original research. Responsible for participating in a research project associated with Ph.D. studies and the interpretation of the results of publication. Work is performed under supervision of graduate faculty members with evaluation based on accomplishment of assigned objectives and overall effectiveness of the project. May supervise research and student assistants.Major/Essential FunctionsResearch and Scientific ActivitiesDesign, plan, and conduct independent and collaborative experiments.Analyze and interpret complex datasets related to metabolic and cardiometabolic disease research.Prepare manuscripts, abstracts, and presentations for peer-reviewed publications and scientific meetings.Critically evaluate and synthesize scientific literature.Assist in training and mentoring graduate students, technicians, and trainees.Demonstrate strong interpersonal, organizational, and collaborative skills.Exhibit excellent written and oral scientific communication.Animal Models & In Vivo TechniquesPerform rodent handling, habituation, health monitoring, and husbandry in compliance with IACUC guidelines.Conduct metabolic disease studies using mouse models of obesity, diabetes, cardiometabolic disorders, and fatty liver disease.Perform injections via multiple routes including intraperitoneal, intravenous, subcutaneous, and oral gavage.Perform euthanasia, perfusion, and tissue collection, including liver, adipose tissue, pancreas, skeletal muscle, blood, and other metabolic organs.Assist with metabolic phenotyping studies, diet-induced obesity models, and therapeutic intervention studies.Metabolic & Physiological PhenotypingConduct metabolic phenotyping using Comprehensive Lab Animal Monitoring System (CLAMS®) to assess energy expenditure, food intake, respiratory exchange ratio, and locomotor activity.Perform body composition analysis using EchoMRI-700™.Perform glucose tolerance tests (GTT), insulin tolerance tests (ITT), and metabolic biomarker analysis.Analyze metabolic and physiological datasets, including statistical analysis and data visualization.Molecular & Cellular AssaysCulture and maintain 2D cell lines and 3D organoid models relevant to metabolic and cardiometabolic diseases.Prepare tissue homogenates and isolated cell populations for molecular and biochemical analyses.Perform assays including:Western blottingqPCR and gene expression analysisELISA and multiplex cytokine profilingSeahorse XF metabolic assays for mitochondrial function and cellular bioenergeticsImmunofluorescence and immunohistochemistry (IHC)Confocal microscopy for high-resolution cellular imaging and protein localizationFlow cytometry for immune and metabolic cell profilingPreferred QualificationsApplicants should have earned a Ph.D., Pharm.D./Ph.D., or M.D./Ph.D. in pharmacology, molecular biology, biochemistry, cell biology, metabolism, or a related biomedical discipline within the last five years (or will have earned the degree prior to the start date as determined by the hiring faculty).Candidates should have a documented record of experience in animal models and in vivo techniques, particularly in metabolic disease models such as obesity, diabetes, cardiometabolic disorders, and fatty liver disease. Experience with rodent handling, metabolic phenotyping, tissue collection and dissection (including liver, adipose tissue, heart, brain, hypothalamus, pancreas, skeletal muscle, and blood), and pharmacological intervention studies is desirable.Additional preferred experience includes 2D and 3D cell culture systems, including organoid models; molecular and cellular assays such as Western blotting, qPCR, ELISA, immunohistochemistry, and immunofluorescence; confocal microscopy; and metabolic assays such as Seahorse analysis or metabolomic/lipidomic profiling. Demonstrated ability to work independently, analyze complex datasets, and contribute to scientific publications is highly desirable.Pay StatementCompensation is commensurate upon the qualifications of the individual selected and budgetary guidelines of the hiring department, as well as the institutional pay plan. For additional information, please reference the institutional pay plan website at StatementAll qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, age, disability, genetic information or status as a protected veteran.Required QualificationsPh.D. or equivalent doctorate (e.g., D.Sc., M.D.) in area of project specialization. Knowledge of modern research practices, the methods, resources, and standards thereof. Ability to organize work effectively, conceptualize and prioritize objectives and exercise independent judgment based on an understanding of organizational policies and activities. Ability to integrate resources, policies, and information for the determination of procedures, solutions and other outcomes. Ability to establish and maintain effective work relationships with other employees and the public. Ability to plan and allocate the workload of employees, providing direct training and supervision as needed. In accordance with Texas Executive Order GA-48 and applicable state or federal law, this position may involve access to, work on, or conduct research involving critical infrastructure. It will require background checks, including, but not limited to, criminal history and other security-related screenings. Employment is contingent upon the successful completion of these checks.Jeanne Clery ActThe Jeanne Clery Disclosure of Campus Security Policy and Campus Crime Statistics Act is a federal statute requiring colleges and universities participating in federal financial aid programs to maintain and disclose campus crime statistics and security information. By October 1 of each year, institutions must publish and distribute their Annual Campus Security Policy & Crime Statistics Report (ASR) to current and prospective students and employees. To view this report, visit the TTUHSC Clery Act website at recognized as a Great College to Work For, TTUHSC provides much more than just a job! Enjoy excellent benefits, including paid leave, retirement plans, wellness programs, health insurance and so much more. Ready to start building a rewarding career in a positive environment where you can develop and thrive? Join us as we change the future of health care.About TTUHSCTexas Tech University Health Sciences Center is enriching the lives of others by educating students, providing excellent patient care, and advancing knowledge through innovative research. TTUHSC graduates more health care professionals than any other health care institution in the state, conferring 24.2% of all degrees and certificates awarded from health-related institutions in Texas. By providing comprehensive clinical services to more than 10 million individuals across 121 counties, TTUHSC is dedicated to advancing the health of people throughout Texas and beyond. This is where world-class education meets compassionate patient care - and we believe that our people are the reason for our institution's lasting success and bright future.Being part of the TTUHSC team means being part of an innovative and supportive community that empowers each individual to do their best work. Through our values-based culture, TTUHSC is committed to cultivating an exceptional workplace community with a positive culture that puts people first.BenefitsTTUHSC is committed to creating an environment where our team members can do their best work, with programs and benefits to support head-to-toe well-being. Explore just a few of the advantages of being a TTUHSC team member:Health Plans + Supplemental Coverage Options - Individual health insurance provided at no cost for full-time team membersPaid Time Off - Including holidays, vacation, sick leave and moreRetirement PlansWellness ProgramsCertified Mother-Friendly WorkplaceAdditionally, TTUHSC invests in the success of our team members by providing opportunities for personal and professional growth, including lifelong learning programs, recognition programs, and health and wellness initiatives. Team members also enjoy a variety of other perks, such as special membership rates at local gyms and golf courses, access to state-of-the-art software and facilities, and discounts on travel, technology, entertainment and more.