Job Posting DescriptionA research assistant position available in the Osterweil lab Boston Children's Hospital beginning Spring of 2026. The individual will join a fast-paced translational team that uses human brain slice and rodent models to study neurological disease (/). During the assistantship, the candidate will contribute to projects using advanced molecular and cellular techniques (scRNA-seq, TRAP-seq), electrophysiology, and 2-photon GCAMP calcium imaging, and acquire the skills needed to perform and analyze experiments. They will be a full member of collaborations with academic investigators as well as clinician scientists focused on treatments for neurodevelopmental disorders. The candidate will be expected to present regularly at laboratory meetings and will have the opportunity present their research at local and national conferences and will be included in publications resulting from their efforts.The position will focus on supporting research on identifying the mechanistic underpinnings of neurodevelopmental disorders. The candidate will be involved in projects developing human brain slices models and identifying molecular, physiological and behavioral changes in mouse models.Duties & Responsibilities will include:Facilitation of human tissue collectionPreparation and maintaining culture of brain slicesImmunohistochemistry and confocal imagingMaintenance of mouse colonies, including breeding and genotypingAssisting in mouse behavioral tasks and in vivo electrophysiologySupport of laboratory operations (ordering supplies, equipment maintenance, laboratory representation in institutional groups, animal protocol upkeep)Qualifications:A BA/BS degree in Biology/Molecular Biology/Biochemistry/Neurobiology or related fieldPast research experience in pharmacology, cell or molecular biology, genetics, or neuroscience at the undergraduate level or beyond, preferred.Experience with either electrophysiology or calcium imaging OR rodent colony management and intracranial surgery is a plusExcellent interpersonal skills, communication, organization, time management, and record-keeping skills a must
Job Title
Research Assistant II