Job Title

Organization Overview The Heintz laboratory investigates the molecular logic that governs cellular function and dysfunction in the mammalian cerebrum. While classical neuroanatomy has defined the structural complexity of the brain with remarkable precision, the molecular mechanisms that orchestrate cell-to-cell interactions and maintain cerebral architecture remain incompletely understood. Our work focuses on uncovering these mechanisms at cell-type resolution, with a particular emphasis on how their disruption contributes to neurodegenerative disease. We integrate advanced genomic, epigenomic, and cell isolation approaches to study human brain tissue directly, enabling mechanistic insight into disorders such as Alzheimers and Huntingtons disease. Overview We are seeking a full-time Research Assistant to support projects dissecting the circuitry and synaptic mechanisms of motivated behavior in animal models. The successful candidate will contribute to animal colony management, behavioral testing, histology, and immunostaining, and will work closely with senior lab members on ongoing experiments. Responsibilities Responsibilities include: + Maintain and manage a transgenic animal colony, including breeding, weaning, genotyping, and record keeping in compliance with institutional animal care guidelines. + Perform perfusion, brain extraction, tissue processing, cryo or vibratome sectioning, immunostaining, mounting, fluorescence imaging, and image quantification to visualize neuronal populations and activity markers. + Conduct and assist with behavioral assays in mice (e.g., reward- and avoidancebased paradigms), including setup, running, and basic analysis of behavior. + Maintain detailed electronic records of experimental procedures, animal lines, and results; contribute to data organization and quality control. + Participate in weekly lab meetings, journal clubs, and training sessions; assist with general lab maintenance and ordering as needed. Qualifications Required Qualifications: + Bachelor of Science degree in Neuroscience, Biology, Psychology, or a related field + Prior experience working in a research laboratory and some familiarity with animal handling or behavioral experiments strongly preferred. + Comfort working with rodents and readiness to learn new behavioral and surgical techniques. + Strong organizational skills, attention to detail, and ability to maintain accurate records and follow standard operating procedures. + Excellent communication skills and the ability to work both independently and as part of a collaborative team in a fast-paced research environment. Preferred Qualifications: + Previous experience with animal colony management (breeding, genotyping) and behavioral testing. + Experience with immunohistochemistry, confocal or widefield fluorescence imaging, and basic image analysis. + Familiarity with basic molecular biology (PCR, DNA/RNA handling) and quantitative data analysis. The Rockefeller University is an equal opportunity employer veterans/individuals with disabilities. Qualified applicants will receive consideration for employment without regard to characteristics protected by applicable local, state or federal law, including but not limited to disability and protected veteran status. The salary of the finalist selected for this role will be set based on various factors, including but not limited to organizational budgets, qualifications, experience, education, licenses, specialty, and training. The hiring range provided represents The Rockefeller University's good faith and reasonable estimate of the range of possible compensation at the time of posting. Compensation Range: Min USD $50,000.00/Yr. Compensation Range: Max USD $55,000.00/Yr.